About DeSoto County
DeSoto County is a city located in United States, in the Mississippi region. According to the latest available data (2026), the population of DeSoto County is approximately 185,314 residents, making it the #436 most populous city in United States.
Globally, DeSoto County ranks #9,426 among the world's most populated cities.
DeSoto County City Statistics
| City | DeSoto County |
| Country |  United States |
| Population | 185,314 |
| Global Rank | #9,426 |
| Rank in United States | #436 of 867 cities |
| City Category | city |
| Region | Mississippi |
| Latitude | 34.88 |
| Longitude | -89.99 |
| Data Year | 2026 |
Where is DeSoto County Located?
DeSoto County is located in United States, in the Mississippi region, at coordinates 34.88° latitude and -89.99° longitude. DeSoto County sits in the subtropics, typically enjoying warm temperatures year-round.
Nearby Cities
Other Cities in United States
Largest Cities in United States
| # | City | Population |
|---|---|---|
| 1 | Harris County | 4,731,145 |
| 2 | Los Angeles | 3,898,747 |
| 3 | San Diego County | 3,298,634 |
| 4 | Brooklyn | 2,736,074 |
| 5 | Miami-Dade County | 2,701,767 |
Frequently Asked Questions
What is the population of DeSoto County?
The population of DeSoto County is approximately 185,314 residents according to the latest available data (2026).
Where is DeSoto County located?
DeSoto County is located in United States at approximately 34.88° latitude and -89.99° longitude.
Is DeSoto County one of the largest cities in United States?
With a population of 185,314, DeSoto County is one of the notable urban areas in United States. It ranks #436 out of 867 cities in the country.
